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pmlR pmlR pmlI pmlI BPSS1180 BPSS1180 BPSS1570 BPSS1570 BPSL1253 BPSL1253 BPSS0886 BPSS0886 BPSS1160 BPSS1160 BPSS0675 BPSS0675 BPSS1358 BPSS1358 wzt2 wzt2 tsr tsr
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pmlRN-acylhomoserine lactone dependent regulatory protein; Similar to Ralstonia solanacearum transcriptional activator protein SolR SWALL:SLR2_RALSO (SWALL:O30919) (236 aa) fasta scores: E(): 2.2e-66, 67.79% id in 236 aa, and to Burkholderia cepacia transcriptional activator CepR SWALL:Q9ZIU0 (EMBL:AF019654) (239 aa) fasta scores: E(): 2.7e-81, 79.91% id in 239 aa. (239 aa)    
Predicted Functional Partners:
pmlI
N-acylhomoserine lactone synthase; Similar to Ralstonia solanacearum autoinducer synthesis protein SolI SWALL:SLI2_RALSO (SWALL:O30920) (204 aa) fasta scores: E(): 5.5e-51, 65.82% id in 199 aa, and to Burkholderia cepacia acyl homoserine lactone synthase CepI SWALL:Q9ZIU1 (EMBL:AF019654) (202 aa) fasta scores: E(): 6.6e-64, 76.84% id in 203 aa.
 
 
 0.992
BPSS1180
N-acylhomoserine lactone synthase; Similar to Burkholderia pseudomallei acyl homoserine lactone synthase BpsI SWALL:AAM21707 (EMBL:AF501236) (203 aa) fasta scores: E(): 1.4e-32, 48.7% id in 193 aa, and to Burkholderia cepacia AHL synthase CepI SWALL:Q9AM55 (EMBL:AF330014) (202 aa) fasta scores: E(): 8.6e-35, 47.8% id in 205 aa.
 
 
 0.977
BPSS1570
N-acylhomoserine lactone synthase; Similar to Burkholderia multivorans N-acyl homoserine lactone synthase SWALL:Q93NN9 (EMBL:AF364058) (202 aa) fasta scores: E(): 4.5e-23, 43.97% id in 191 aa, and to Burkholderia cepacia N-acyl homoserine lactone synthase cepI SWALL:Q9AM52 (EMBL:AF330017) (202 aa) fasta scores: E(): 8.3e-23, 44.19% id in 181 aa.
 
  
 0.765
BPSL1253
Putative integral membrane protein/sensor kinase; N-terminal region similar to Ralstonia solanacearum probable transmembrane protein rsp0132 or rs02988 SWALL:Q8XTH8 (EMBL:AL646076) (478 aa) fasta scores: E(): 1.6e-45, 48.28% id in 292 aa, and C-terminal region similar to Erwinia amylovora sensor kinase HrpX SWALL:Q9X3S8 (EMBL:AF083877) (494 aa) fasta scores: E(): 6.6e-24, 41.35% id in 237 aa.
 
 
 0.581
BPSS0886
Hypothetical protein; Poor database matches. Weakly similar to the N-terminal region of Rhizobium meliloti hypothetical protein rb0634 or smb21055 SWALL:Q92VR5 (EMBL:AL603644) (194 aa) fasta scores: E(): 1.3, 31.34% id in 134 aa.
     
 0.580
BPSS1160
Similar to Bacillus subtilis sensor protein DegS or SacU SWALL:DEGS_BACSU (SWALL:P13799) (385 aa) from codon 330 fasta scores: E(): 5.1e-18, 29.48% id in 329 aa, and to Ralstonia solanacearum probable transmembrane two component system sensor kinase transcription regulator protein rsc0191 or rs00623 from codon 202 SWALL:Q8Y2Z0 (EMBL:AL646057) (458 aa) fasta scores: E(): 4.3e-49, 49.12% id in 458 aa. No transmembrane regions are predicted.
 
 
 0.572
BPSS0675
GerR family regulatory protein; Similar to Burkholderia cepacia genomovar III putative regulatory protein SWALL:Q8VP25 (EMBL:AY028431) (302 aa) fasta scores: E(): 7.8e-78, 66% id in 303 aa. C-terminal region is similar to Pseudomonas aeruginosa transcriptional activator protein LasR SWALL:LASR_PSEAE (SWALL:P25084) (239 aa) fasta scores: E(): 4.6e-05, 25.1% id in 243 aa.
 
 
 0.547
BPSS1358
Putative sensor kinase protein; Similar to Erwinia chrysanthemi regulator HrpX SWALL:AAM46691 (EMBL:AF448202) (450 aa) fasta scores: E(): 8.4e-24, 28.46% id in 390 aa, and similar to the C-terminus of Pseudomonas aeruginosa probable two-component sensor pa0600 from codon 129 SWALL:Q9I5T8 (EMBL:AE004496) (797 aa) fasta scores: E(): 1.2e-36, 38.79% id in 366 aa, and to similar to the C-terminus of Ralstonia solanacearum probable transmembrane two component system sensor kinase transcription regulator protein rsc0191 or rs00623 from codon 254 SWALL:Q8Y2Z0 (EMBL:AL646057) (458 aa) fasta sc [...]
 
 
 0.519
wzt2
Putative ATP-binding ABC transporter capsular polysaccharide export protein; Similar to Haemophilus influenzae ATP-binding protein BexA SWALL:BEXA_HAEIN (SWALL:P10640) (217 aa) fasta scores: E(): 2.7e-42, 58.98% id in 217 aa. Highly similar to Burkholderia mallei putative ABC-2 transporter Wzt SWALL:Q9AI45 (EMBL:AF285636) (218 aa) fasta scores: E(): 5.1e-73, 100% id in 218 aa. Previously as sequenced Burkholderia pseudomallei putative ATP-binding protein Wzt2 SWALL:Q93UJ9 (EMBL:AF228583) (248 aa) fasta scores: E(): 3.3e-70, 99.05% id in 211 aa.
      
 0.497
tsr
Similar to Escherichia coli methyl-accepting chemotaxis protein I Tsr or CheD or b4355 SWALL:MCP1_ECOLI (SWALL:P02942) (551 aa) fasta scores: E(): 9e-44, 42.88% id in 541 aa.
      
 0.471
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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